Cross-species matings
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In a few science fiction series (the Star Trek Franchise being the most notable), humans, can have sex with extra-terrestrial species and produce young. This is, of course, absolutely ridiculous. Even taking into account the possibility of Panspermia, a human would have more in common genetically with a tulip than with an extra-terrestrial.
Species are defined by their inability to cross breed.
Notable products of cross-species matings include: