Kes
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Kes was an Ocampan female, who spent three years on the USS Voyager. She did little of note during her time on Voyager, aside from nearly killing Tuvok on more than one occasion, eating some beetles, and being the girlfriend of Neelix for a short while before dumping him.
Shortly after being in telepathic contact with Species 8472, the occasional psychic powers Kes displayed suddenly and inexplicably increased to a massive degree, forcing her to leave the ship. Afterwards, she "evolved" into a non-corporeal life form (although as usual, the process had no resemblance to real-world evolution), and finally did something useful for Voyager, propelling the ship 10,000 light-years closer to Earth, conveniently bypassing Borg space.
Some years later, she again underwent an inexplicable change, "de-evolving" back into an Ocampan with powerful psychic abilities and anger management issues. Despite coming up with a bizarre plan to get herself killed in the past by handing Voyager over to the Vidiians, Janeway talked her out of it, and Kes took a shuttle back to the Ocampa homeworld, never to be seen again.
Blind as a bat
She once stated she didn't think Janeway was stupid and that the genocidal bitch actually cared about her crew.[1]